P-Rex1 is a novel substrate of the E3 ubiquitin ligase Malin associated with Lafora disease
Laforin and Malin are two proteins that are encoded by the genes EPM2A and Neff D85IBE1S0B Chimney Cooker Hood A Energy Rating Black EPM2B, respectively.Laforin is a glucan phosphatase and Malin is an E3-ubiquitin ligase, and these two proteins function as a complex.Mutations occurring at the level of one of the two genes lead to the accumulation o